by Ben Sensi on 07/08/2012 | Consumption

Cannabis and its effects on metabolism

Researchers have discovered two cannabinoids that can increase the amount of energy the body burns

Although cannabis is better known for inducing hunger in those who smoke it, known as the munchies, scientists have found that it can also have an appetite suppressing effect after examining two compounds, called tetrahydrocannabivarin (THCV) and cannabidiol (CBD).

“The results in animal models have been very encouraging. We are interested in how these drugs affect the fat distribution and utilisation in the body as a treatment for metabolic diseases.”, commented Dr. Steph Wright, Director of research and development at GW Pharmaceuticals.

Tests in mice showed the compounds boosted the animals’ metabolism, leading to lower levels of fat in their livers and reduced cholesterol in their blood stream. THCV was also found to increase the animals’ sensitivity to insulin while also protecting the cells that produce insulin, allowing them to work better and for longer. It has raised hopes that the drugs can be developed into treatments for obesity related diseases and type 2 diabetes. GW Pharmaceuticals will now start phase IIa of testing and is already working on a variety of marijuana-based drugs for the treatment of multiple sclerosis, epilepsy, cancer, pain, and other conditions.

tetrahydrocannabivarin (THCV)
tetrahydrocannabivarin (THCV)



Professor Mike Cawthorne, director of metabolic research at the University of Buckingham who has been conducting the animal studies, said: “Overall, it seems these molecules increase energy expenditure in the cells of the body by increasing the metabolism.”

The United Kingdom is the second most obese country in the world, trailing the United States where 35.7% of adults are classified as obese; a significant percentage of children have been diagnosed as obese as well. With the prevalence of fast food conglomerates, obesity is becoming an increasingly difficult issue in the developing world as well.


“These findings are extremely important, especially when it comes to comparing marijuana and alcohol,” said Rob Kampia, executive director of the Marijuana Policy Project in Washington, D.C. in reaction to the findings. “Marijuana is obviously safer than alcohol, but now I understand why I gained 25 pounds when I stopped using marijuana but continued to use alcohol, beyond the fact that alcohol contains calories, while marijuana contains none. To now find out that marijuana’s molecular structure can actually help with obesity and related diseases is wonderful, but it’s also infuriating when one thinks about the Obama administration’s continued attacks on medical marijuana. If the First Lady is really concerned about obesity in America, she should tell her husband to stop interfering with state medical marijuana laws and research. After all, heart disease, stroke, and diabetes kill hundreds of thousands of people in this country every year. Marijuana kills exactly zero.”

Source: The Telegraph

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we could not afford it, as govt would tax what is already a rich mans choice of drug.



Grow it yourself! That's the point!



Actually, if we want to see the people, and the plant released from the bondage of prohibition, then we need to concentrate on the tree words that illustrate the entire solution fo the problems of this sorry chapter of global prohibition of cannabis/hemp:

1) DEschedule.
2) Repeal.
3) DONE!!!



Marijuana -the dried herb- is no more medicinal than opium. After botanical extraction and refinement, we'll surely develop very useful med's. However, the rest of us need to stop being dillusional as world wide stoners. The moment you can buy marijuana at the gas station no mom and pop business will survive - Marlboro has had 200 acres+ set aside for marijuana for more than 15 years. It will be chalked full of additives and all the profits will go to the same 1% who are getting everything now.

I submit, we start pushing legalization of seed stock, legalization of growing all the plants you want. Illegalization of marijuana for trade. You can't buy it, if you want it grow your own. And as for seed stock, much easier to tax and moderate. After all, its much harder to produce quality seeds than quality marijuana. Yet you have an exponentially higher profit margin as quality seeds go for the same unit price as marijuana herb by the gram. But you get thousands of seeds to every hundred grams of herb.

Leave medicine to science and take money out of the equation. Health already is.
My two cents



Cannabis must really be special! The USA relies upon outdated,racist,corrupt arguments by 1937 government officials and certain industrialists and newspaper moguls along with bad and new science which just confirms what 5,000 years of medical documentation knew all along.
What court would rule in favor of the USA?
What other issue or subject or societal/medical question be "answered" by such outdated,corrupted and proven-wrong data?
USA,you are NOT bigger than the World,in spite of your delusional beliefs.
Free cannabis for all! Legalize now.Or at least move to schedule III,that is if you have a modicum of decent honesty left!



Hello,I am from USA,I do not think we are bigger then the world,just the politicos do.I am a victim of the war on drugs here,and I fully support full legalization of the plant.The plant has never in and of itself harmed 1 person in thousands of years.
But the pols in power will not allow that to happen they have to much money invested in the corrupt private for profit penal systems.It is all about money over here.If the plant is legalized then i twould mean less profits for the ones in charge.So it will never be defacto legal here.Im waiting on the USSA to start taxing the air we breathe,they will tav everything else except marijuana,they make too much money off of it being illegal to make it legal.
So I continue my fight with the rest of the ppl here to make it legal.Please lets not blame the countries,its the ppl in power that have the control,not the citizens themselves.



Ganja is legal! Governments are not!



Hey guys I just saw this study... Seems one of the greatest job last five years... Freedom forever...

Bodyguard for the Brain: Researchers Identify Mechanism That Seems to Protect Brain from Aging



i bud you alllllllll



I don't like this news.......



Do someone remembers the name of the country who wanted to legalize cannabis , and than to put the monopoly of the state upon it. I think it was the Uruguay . It is about one year I think this is the great solution ! Good Bye . . .



i think the thought of this holy herb being legalized in the world sounds nice but its the only thing our gov havnt gotten their stinky hands on and it should stay tht way if they get involved its gonna be a disaster for all respected stoners,herbz would never be the same so plz as much as we would like it,its only going to complicate our eeeezy stoning life,so embrace the weeds peolple JAH!!



Legalize today, medicate tonight. Kent is half-right about the politicians. You can vote for someone like Obama who said he would not
interfere with medical cannabis in the usa, but then he stabs the medical community in the back. All we can do is vote for politicians we can trust. It's like choosing between tweedle-dee and tweedle-dumb.
I prefer the lesser of two evils myself. At least the drug nazi's are honest in their hatred of the cannabis plant and the patients who use it for their illnesses. There is a scripture in the King James Bible that applies to this situation.
" A known foe is a curse, but a pretend friend is worse" No matter who gets elected, I'm going to use cannabis and I don't live in a medical state. The only way they can stop me is to jail me and it's available in jail or assasinate me. I just regret I haven't been able to go to the cannabis cup since 2007 and the politicians in Holland are trying to go backward instead of forward and screw up a great system.


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