1. In cannabis cultivation a cola is the part of a female cannabis plant where the flowers or buds grow together tightly at the tip of the plant stem. The botanical term for this is the terminal bud. Healthy plants usually form one main cola from the centre of the rhisomatic structure, with smaller colas forming around the outside. Various training and trimming techniques can be used to increase the amount of large colas that a plant will form, which increases the yield of usable material. 2. A carbonated soft drink containing an extract made from kola nuts (as in Coca-Cola), 3. The plural of colon.